Leslie
Eleazer Orgel FRS (12 January 1927 – 27 October 2007) was a British chemist.
Born in
London, Orgel received his B.A. and Ph.D in chemistry at Magdalen College,
Oxford University.
He was one
of the first people to see, in April 1953, Crick and Watson's model of DNA: at
the time he worked at Oxford University's Chemistry Department.[1]
In 1964
Orgel was appointed Senior Fellow and Research Professor at the Salk Institute
for Biological Studies, where he directed the Chemical Evolution Laboratory. He
was also an adjunct professor in the Department of Chemistry and Biochemistry
at theUniversity of California, San Diego, and he was one of five principal
investigators in the NASA-sponsored NSCORT program inexobiology. Orgel also
participated in NASA's Viking Mars Lander Program as a member of the Molecular
Analysis Team that designed the gas chromatography mass spectrometer instrument
that robots took to the planet Mars.
Orgel’s lab
came across an economical way to make cytarabine, a compound that is one of
today’s most commonly used anti-cancer agents.
During the 1970s, Orgel suggested reconsidering the
panspermia hypothesis, according to which the earliest forms of life on earth
did not originate here, but arrived from outer spacewith meteorites.
Together with Stanley Miller, Orgel also suggested that
peptide nucleic acids – rather than ribonucleic acids – constituted the first
pre-biotic systems capable of self-replication onearly Earth.
His name is popularly known because of Orgel's rules,
credited to him, particularly Orgel's Second Rule: "Evolution is cleverer
than you are".
In his book The Origins of Life, Orgel coined the concept of
specified complexity, to describe the criterion by which living organisms are
distinguished from non-living matter. He published over three hundred articles
in his research areas.
Orgel died
of cancer on 27 October 2007 at the San Diego Hospice & Palliative Care in
San Diego, California
~ Isaac González
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